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SERVICES > INFUSIONS > NAD+ IV INFUSION

NAD+ IV Infusion

Nicotinamide Adenine Dinucleotide — the Coenzyme at the Center of Every Cell's Energy Production, DNA Repair, and Anti-Aging Pathway

DURATION: Variable by dose — NAD+ infusions run slowly to minimize side effects. Allow 1–2 hours for lower doses and 3–4 hours for higher doses. Your nurse will set the appropriate rate at your session.
NAD+ IV infusion treatment for energy and wellness support at Vitality IV

Quick Benefit Highlights

  • The Coenzyme Behind Every Cell’s Energy and Repair: NAD+ is required for over 500 enzymatic reactions in the body — including the reactions that produce ATP in the mitochondria, the reactions that repair damaged DNA, and the reactions that regulate the sirtuins and PARP enzymes now at the center of longevity science
  • Levels Decline With Age — and IV Replacement Is the Most Impactful Way to Restore Them: NAD+ levels fall by approximately 50% between the ages of 40 and 60, and continue declining thereafter. This decline is directly linked to the reduced cellular repair capacity, metabolic inefficiency, and cognitive slowing that accompany aging. IV NAD+ raises serum levels immediately and significantly in a way that oral precursors cannot match for speed or magnitude
  • A Breadth of Recognized Benefits Supported by Published Research: Clinical and preclinical evidence associates IV NAD+ with improvements in mental clarity, energy, mood, athletic performance, metabolic function, and recovery from addiction and long-COVID — a scope of benefit that reflects how fundamental NAD+ is to virtually every system in the body
  • Four Dosages for Four Levels of Need: From the 250mg introductory dose to the 1000mg high-potency protocol, Vitality Infusions offers the full dosage range used in NAD+ therapy — so your protocol can be matched to your goals, your timeline, and your experience with the treatment

Every Cell in Your Body Runs on NAD+.
What Happens When You Start Running Low?

Nicotinamide adenine dinucleotide is not a vitamin or a supplement in the conventional sense. It is a coenzyme — a molecule that sits at the center of hundreds of biochemical reactions in every cell of the body, enabling them to occur. Without adequate NAD+, these reactions slow down, stall, or fail entirely. And unlike most nutrients, NAD+ declines not from dietary insufficiency alone but as a direct consequence of biological aging — with levels dropping by roughly half between the ages of 40 and 60 regardless of how well a person eats or lives.

The implications of this decline are broad and compounding. At the mitochondrial level, lower NAD+ means less efficient conversion of nutrients into ATP — the cellular energy currency that powers every process in the body. At the genomic level, lower NAD+ means slower activation of the PARP enzymes that detect and repair DNA strand breaks, allowing cellular damage to accumulate faster than it can be corrected. At the regulatory level, lower NAD+ means reduced activation of the sirtuins — a family of proteins that govern gene expression, stress response, inflammation control, and the biological aging rate itself. The result of all three declining simultaneously is what most people experience simply as getting older: lower energy, slower recovery, reduced cognitive sharpness, and a body that repairs itself less efficiently than it once did.

IV NAD+ administration bypasses the intestinal conversion steps required by oral NAD+ precursors like NMN and NR, delivering the active coenzyme directly into the bloodstream at concentrations that produce immediate cellular effects. The response many clients experience during and after their NAD+ infusion — a distinctive mental clarity, a sense of cellular aliveness, and an energy that feels fundamentally different from a caffeine or stimulant effect — reflects the direct biochemical impact of restoring the coenzyme the body’s most critical processes depend on.

NAD+ Has Been Found To:

  • Reduce stress, depression, and anxiety through its role in neurotransmitter synthesis and sirtuin-mediated neuroprotection
  • Improve post-COVID symptoms including brain fog, fatigue, and exercise intolerance by restoring mitochondrial energy production in depleted cells
  • Improve mental clarity, alertness, concentration, and memory through the NAD+-dependent pathways that support neuronal function and synaptic health
  • Increase metabolism and energy by restoring the efficiency of the mitochondrial reactions that produce ATP from nutrients
  • Reduce symptoms of withdrawal from alcohol and certain substances by supporting the neurochemical repair processes that addiction depletes
  • Reduce signs of aging by activating sirtuin-mediated DNA repair, reducing cellular oxidative damage, and supporting the telomere maintenance pathways associated with biological longevity
  • Restore muscle function and athletic performance by improving mitochondrial energy availability and reducing the oxidative damage that impairs muscle cell repair

Ideal For:

  • Adults over 35 who want to proactively address the NAD+ decline that accompanies aging before its effects become pronounced
  • Anyone experiencing persistent fatigue, brain fog, or cognitive slowing that has not responded to standard wellness protocols
  • Those managing post-COVID symptoms including long-haul fatigue, cognitive impairment, and reduced exercise capacity
  • Athletes and high-performance individuals who want to optimize mitochondrial energy production and recovery at the cellular level
  • Clients focused on longevity, cellular anti-aging, and the long-term protection of cognitive and physical function
  • Those in recovery from alcohol or substance dependence who want neurochemical repair support as part of their protocol
  • Anyone who has plateaued on conventional wellness approaches and wants to address the cellular energy and repair layer directly

How You’ll Feel:

NAD+ infusions are among the most distinctively experiential treatments on our menu. During the infusion itself, particularly at higher doses, clients commonly report a building sense of mental clarity, a subtle warmth or pressure in the chest that passes as the rate is adjusted, and a quality of aliveness that is difficult to describe but immediately recognizable. In the 24 to 72 hours following a session, clients consistently report sharper cognition, elevated and stable mood, significantly improved energy, and a sense of physical and mental restoration that accumulates with successive infusions. Many clients describe their first high-dose NAD+ infusion as one of the most impactful wellness experiences of their lives.

Service Details

What to Expect: Your Session

  1. Consultation and Dosage Selection: Your nurse reviews your health history, current goals, and any prior NAD+ experience to confirm the appropriate dosage for your session. First-time clients receive a full overview of what to expect during the infusion including the chest pressure sensation and how the infusion rate will be managed.
  2. Comfortable Setup: Settle into our heated massage chair or your mobile location. NAD+ sessions run longer than standard infusions — bring something to watch, read, or listen to. Your nurse places the IV catheter and begins the infusion at a rate appropriate for your dose.
  3. Your Infusion Session (1–4 Hours Depending on Dose): Your nurse monitors you closely throughout, particularly in the early stages of the infusion. If you experience chest pressure, flushing, or nausea, let your nurse know immediately and the rate will be reduced. Most clients find a comfortable rate within the first 45 minutes and the remainder of the session proceeds smoothly. Many report the distinctive clarity and aliveness of NAD+ building progressively as the session continues.
  4. Post-Infusion: Catheter out and you are free to go. Many clients experience the most significant benefit in the 24 to 48 hours following their session as NAD+ levels stabilize and cellular processes responding to the restored coenzyme pool begin to show results. Plan to be well-rested and well-hydrated in the day following your infusion.
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Schedule a visit to our Ft. Myers lounge or order mobile delivery for premium IV therapy, customized for your health and wellness goals.

GOOGLE REVIEWS

See What Others Are Saying Online

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Edward Metzger
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TARA AT THE FT MYERS LOCATION IS TERRIFIC - PROFESSIONAL AND FUN TO BE AROUND
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Beckie R.
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This place has helped me through my worst health moments when the medical system wasn't enough. All of the nurses have been great. I love this place.
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Blah
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Bro oml ts was fye bro like there were pineapples in the fridge iPad they was fye🍠🤤🔥 I drank sum the fluid juice and now I pee gray sludge but it’s aight the pineapples was bussin🔥🔥🤤 later today ima watch jjk and eat more pineapples❤️🤤
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Steph
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Absolutely amazing experience. Kind, caring and knowledgeable. I was having an issue where I became extremely dehydrated and needed IV fluids. They also have zofron ( for nausea) wich is amazing. If you have ever needed it you know. I can't recomend them enough. Invest in yourself as I immediately felt better after my IV bag. Very clean,nice,convenient location. You can sit & relax in a recliner while your IV drips or they have a private room in the middle. The price is pretty good especially considering it against perhaps an ER visit. I highly recommend this place. You won't be disappointed.
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Paola Perez
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Great service and staff. I received an NAD+ shot and B12 shot and felt amazing. Great place to come and receive your IV therapy.
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John D
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First class service and very extensive infusion options. I found them out at a pickle ball tournament taking care of us players, giving out some free IVs and B-12 shots, which was greatly appreciated in the heat. I played my next match feeling 100 percent again post IV. Thanks again, Mindy! You’re amazing at what you do!!
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Blaize French
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My wife just gave birth to our 1st born was feeling dehydrated and The owner of the company came to our house and helped her feel new again. Very professional, knowledgeable, and friendly! Definitely gonna recommend to friends and family.
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Cassidy Dameron
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Quick, easy, and painless! I have POTS and was experiencing more symptoms than usual, so I went to Vitality for the first time for an IV drip. The owner was extremely nice and answered all of my questions. An easy go-to place for reliable IV treatment.

Your Cells Have Been Waiting for This. The Most Powerful Cellular Renewal Protocol We Offer.

Book your NAD+ Infusion at either of our Fort Myers lounge locations or via mobile delivery throughout Lee, Collier, and Charlotte County. Select your dosage at booking. First-time clients are encouraged to call to discuss the right starting dose before booking.